The genus Turbinaria is a chemically diverse group of seaweeds containing several phytochemicals with unique pharmacological activities useful in the treatment and management of diseases. This study was done to evaluate the bioactive potential of a brown macroalga, Turbinaria decurrens Bory from Pagkalitan, Batangas. This investigation is one of the pioneering research studies in the Philippines showing the potential of T. decurrens extract as a cheap source of biologically active compounds with potential use for the treatment of drug-resistant bacterial infection and diabetes.