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Quantitative Trait Loci (QTL) Maps for Crop Disease Resistance Development
Quantitative trait loci (QTL) involves the construction of genome maps and the search for an association between economically-important traits and polymorphic markers. QTL mapping has several important applications in understanding the genetic basis of quantitatively controlled resistance. The role and contribution of a specific locus in disease resistance can be described by determining the degree of association between a particular DNA-based marker and quantitative resistance locus. Applications of the QTL maps include generation of disease-resistant crop varieties, increased efficiency of crop breeding programs through marker-assisted selection; and map-based and positional cloning of resistant genes that can be transferred to other high-value crops to provide the same level of resistance against pest and diseases. End-users of this technology are the researchers who will use marker-aided breeding procedures and pest and disease-resistant genetic stocks. QTL maps for various crop diseases have been developed for downy mildew and bacterial wilt resistance in corn; bacterial wilt resistance in tomato; thrips resistance in potato; cercospora leaf spot, druchid resistance and drought tolerance in mungbean.
DNA technology
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