Seaweeds are a rich source of active compounds with excellent biological activities that are useful for formulation of cosmetic products. The investigation aims to study the biological and skin protection activities of Sargassum ilicifolium extract by evaluating its ability to scavenge free radicals, copper reducing capacity, tyrosinase inhibition and antibacterial properties. This study clearly demonstrates the effective biological and skin protecting properties of Sargassum ilicifolium as an alternative source of active ingredients useful for cosmeceutical application.